Breast Cancer: High‐Dose Therapy

Molecular mechanisms involved in multidrug resistance in breast cancer therapy

Breast cancer is the most prevalent cancer in women. Chemotherapy is the main strategy in the treatment of this disease especially in the advanced form of the disease. Despite the recent progress in the development of new chemotherapy, the effectiveness of these drugs has dramatically reduced due to multidrug resistance. The phenotype of multidrug resistance (MDR) can occur through different me...

Metacognitive Therapy and Depression of Women with Breast Cancer

Objective: This study aimed to examine the effectiveness of metacognitive therapy on decreasing depression in women with breast cancer. A single-case design was employed in this research.  Methods: An AB form of single-subject experimental design was used in this study with 3 baselines (every 10 days) before intervention stage and two measurements during intervention stage and one follow-up ...

Skin Reaction in Radiation Therapy for Breast Cancer

Introduction The first medical intervention for many breast cancer patients is breast conserving surgery (BCS) and/or modified radical mastectomy (MRM). Most of these patients undergo radiation therapy, following surgery. The most common side-effect of breast radiotherapy is skin damage. In the present study, the severity of acute skin changes and the underlying causes were investigated in pati...

Evaluation of Local Recurrence of Breast Cancer after Mastectomy and Breast Preservation Therapy

Abstract Introduction: Breast cancer is the most common cancer among women. Even though mastectomy is known as a highly effective method to treat breast cancer, the percentage of patients with local recurrence is still high. Objective: To determine the incidence of local recurrence after mastectomy and breast preservation surgery. Materials and Methods: Patients with breast cancer that under...

Breast Implants and Breast Cancer